Patent · US Active

Use of gTso thal in manufacturing medicament for promotion of MS-275 to cross blood-brain barrier

US11701338B2 · kind B2 · utility

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0References

12Claims

0Family size

Assignee

Northwest Institute of Plateau Biology, Chinese Academy of Sciences · CN

Inventors

Xiaohui Zhao · Solo Court, CN
Ting Zhang · Shanghai, CN
Huilan Yue · Solo Court, CN
Jihong Tao · Solo Court, CN
Wenjing Jia · Solo Court, CN
Guoying Zhou · Madison, US
Lixin Wei · Solo Court, CN
Chen CHEN · Wuxi, CN

Key dates

Filing date	Aug 7, 2020
Grant date	Jul 18, 2023
Priority date	—
Expiry date	Mar 17, 2041

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K9/48
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to use of gTso thal in manufacturing a medicament for the promotion of MS-275 to cross the blood-brain barrier (BBB), and belongs to the technical field of pharmaceutical preparation. Administration of the medicament manufactured by the use of the present invention in combination with MS-275 significantly increases MS-275 to cross the BBB into the brain tissue, and prominently promotes the accumulation of MS-275 therein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.