Multivalent plant immune fusion protein, production method thereof and its use
US11702454B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 17, 2021 |
| Grant date | Jul 18, 2023 |
| Priority date | — |
| Expiry date | Oct 17, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBasic materials chemistry
- WIPO sectorChemistry
Abstract
The present invention belongs to the field of biotechnology, in particular to a multivalent fusion protein AB-NAC-189, method for producing the same, and uses thereof. The protein AB-NAC-189 is a fusion of a polypeptide segment AB, nascent polypeptide-associated complex (NAC), and a protein 189 corresponding to amino acids 1-189 from the N-terminal of protein HarpinEa. The fusion has the properties of a multivalent plant immune protein, thus it can effectively stimulate the hypersensitive response of tobacco leaves and has good thermal stability. While stimulating the immune response of plants, it can also improve the disease resistance of plants and promote plant growth. The AB-NAC-189 multivalent vaccine shows higher activity per unit concentration, and greater ability to promote growth of wheat and tobacco; meanwhile it can significantly promote chlorophyll synthesis in Goji berry, thereby improving the yield and quality of Goji berries.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.