Automated microdissection instrument and method for processing a biological sample

US11703428B2 · kind B2 · utility

Assignee

• Life Technologies Corporation · US

Inventors

• Thomas M. Baer · Mountain View, US
• Michael Youngquist · Palo Alto, US
• Brian W. Donovan · San Jose, US
• Alan E. Wessel · Mountain View, US
• Norbert Leclerc · Heidelberg, DE
• Michael A. Smith · Phoenix, US
• Craig S. Barker · San Carlos, US
• George M. Dawson · Los Gatos, US

Key dates

• Filing date: Nov 1, 2021
• Grant date: Jul 18, 2023
• Expiry date: Nov 1, 2041

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T156/1054
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Systems and methods for automated laser microdissection are disclosed including automatic slide detection, position detection of cutting and capture lasers, focus optimization for cutting and capture lasers, energy and duration optimization for cutting and capture lasers, inspection and second phase capture and/or ablation in a quality control station and tracking information for linking substrate carrier or output microdissected regions with input sample or slide.