Patent · US Active

Glass vial with increased chemical stability

US11707412B2 · kind B2 · utility

0Cited by

2References

19Claims

0Family size

Assignee

SHOTT Pharma AG & Co. KGaA · DE

Inventors

Robert Frost · Eggersriet, CH
Uwe Rothhaar · Birkenheide, DE
Florence Buscke · Mainz, DE
Bernhard Hladik · Alzey, DE

Key dates

Filing date	Aug 13, 2020
Grant date	Jul 25, 2023
Priority date	—
Expiry date	Jul 5, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC03C23/0075
WIPO fieldMaterials, metallurgy
WIPO sectorChemistry

Abstract

A glass vial includes a base including a boron-containing multicomponent glass and a vial opening and holds a liquid active pharmaceutical ingredient formulation. The glass vial has a total volume of <4.5 mL. A filling level of the glass vial with the active pharmaceutical ingredient formulation is not more than 0.25 and a concentration of boron ions, measured at a measurement site below a plane of a middle of the glass vial using a concentration depth profile at a depth in a range from 10 to 30 nm, has a value, averaged over the measurements of the concentration depth profile, that has an excess increase of not more than 30% compared to a concentration of boron ions measured using a concentration depth profile at a depth in a range from 10 to 30 nm with a measurement site in the plane of the middle of the glass vial.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.