Patent · US Active

Method for preparing (dimethylaminomethylene) malononitrile using a micro reaction system

US11708321B2 · kind B2 · utility

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20Claims

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Assignee

FUDAN UNIVERSITY · CN

Inventors

Fener CHEN · Shanghai, CN
Dang CHENG · Shanghai, CN
Meifen JIANG · Shanghai, CN
Minjie LIU · Shanghai, CN
Huashan HUANG · Shanghai, CN
Lulu Wang · Shanghai, CN

Key dates

Filing date	Nov 24, 2020
Grant date	Jul 25, 2023
Priority date	—
Expiry date	Jan 27, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C255/25
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A method for preparing (dimethylaminomethylene) malononitrile by using a micro reaction system. Cyanoacetamide, N,N-dimethylformamide and a catalyst are mixed to obtain a mixture, and the mixture and phosphorus oxychloride are simultaneously pumped into the micro reaction system that includes a micromixer and a microchannel reactor connected in series for continuous dehydration condensation. After adjusted to a target pH, the crude product is subjected to continuous liquid-liquid extraction with an organic solvent in a centrifugal extraction unit comprising a plurality of annular centrifugal extractors connected in series. The organic phase is collected to obtain the target product (dimethyl aminomethylene) malononitrile.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.