Immunomodulator compounds

US11708326B2 · kind B2 · utility

Assignee

• CHEMOCENTRYX, INC. · US

Inventors

• Christopher W. Lange · Hayward, US
• Viengkham Malathong · Mountain View, US
• Venkat Reddy Mali · Cupertino, US
• Jeffrey P. McMahon · San Francisco, US
• Darren McMurtrie · Daly City, US
• Sreenivas Punna · Sunnyvale, US
• Howard S. Roth · Champaign, US
• Rajinder Singh · Belmont, US
• Yu-Ji WANG · Palo Alto, US
• Ju Yang · Palo Alto, US
• Penglie Zhang · Foster City, US

Key dates

• Filing date: Nov 30, 2020
• Grant date: Jul 25, 2023
• Expiry date: Nov 30, 2040

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein Z, L, R1a, R1b, R1c, R1d, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.