Patent · US Active

Inhibitors of prolyl-tRNA-synthetase

US11708353B2 · kind B2 · utility

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32References
19Claims
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Key dates

Filing dateJun 10, 2019
Grant dateJul 25, 2023
Priority date
Expiry dateSep 28, 2039

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D405/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present application provides compounds, such as compounds of Formula Ia, which are inhibitors of aminoacyl tRNA-synthetase (e.g., prolyl-tRNA-synthetase), and which are useful for treating disorders associated with aminoacyl tRNA-synthetase activity and/or expression. Pharmaceutical compositions comprising the compounds and methods of using the compounds are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.