Patent · US Active

Analogues and derivatives of cephalotaxine and methods for making and using the compounds

US11708377B2 · kind B2 · utility

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26Claims
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Assignee

Inventors

Key dates

Filing dateSep 9, 2021
Grant dateJul 25, 2023
Priority date
Expiry dateApr 1, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D491/20
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Disclosed herein are embodiments of a compound having a Formula I or a salt, solvate, N-oxide, prodrug, diastereomer or enantiomer thereof. Also disclosed are derivative compounds made from the compound of Formula I. Certain derivative compounds have a Formula V-2, or a salt, solvate, N-oxide, prodrug, diastereomer or enantiomer thereof. Also disclosed are method for making and using the disclosed compounds. Certain disclosed embodiments are useful for treating and/or preventing certain diseases and/or disorders, including proliferation diseases, such as leukemia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.