Patent · US Active

Targeted non-invasive imaging probes of EGFR expressing cells

US11708393B2 · kind B2 · utility

0Cited by

53References

7Claims

0Family size

Assignee

CASE WESTERN RESERVE UNIVERSITY · US

Inventors

James Basilion · Cleveland, US
Richard Agnes · Cleveland, US

Key dates

Filing date	Apr 7, 2021
Grant date	Jul 25, 2023
Priority date	—
Expiry date	Dec 15, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K7/56
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A probe for imaging EGFR expressing cells includes an EGFR targeting moiety, a reporter moiety, and a hydrophilic linker that links the EGFR targeting moiety to the reporter moiety. The hydrophilic linker enhances solubility of the probe in an aqueous media as well as binding affinity of the probe to EGFR expressing cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.