System and method for the contextualization of molecules
US11710049B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 24, 2022 |
| Grant date | Jul 25, 2023 |
| Priority date | — |
| Expiry date | Oct 24, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16C20/90
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
A system and method that given one or more input molecules, produces a contextualized summary of characteristics of related target molecules, e.g., proteins. Using a knowledge graph which is populated with all known molecules, input molecules are analyzed according to various similarity indexes which relate the input molecules to target proteins or other biological entities. The knowledge graph may also comprise scientific literature, governmental data (FDA clinical phase data), private research endeavors (general assays, etc.), and other related biological data. The summary produced may comprise target proteins that satisfy certain biological properties, general assay results (ADMET characteristics), related diseases, off-target molecule interactions (non-targeted molecules involved in a specific pathway or cascade), market opportunities, patents, experiments, and new hypothesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.