Patent · US Active

3,3-difluoroallylamines or salts thereof and pharmaceutical compositions comprising the same

US11713308B2 · kind B2 · utility

1Cited by
6References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 6, 2021
Grant dateAug 1, 2023
Priority date
Expiry dateJan 5, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D498/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present technology provides 3,3-difluoroallylamines or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and uses thereof. The 3,3-difluoroallylamines or their pharmaceutically acceptable salts exhibit potent inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.