Claudin-18.2-specific immunoreceptors and T cell epitopes

US11713346B2 · kind B2 · utility

Assignees

• BioNTech Cell & Gene Therapies GmbH · DE
• TRON—Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg-Universität Mainz · DE

Inventors

• Ugur Sahin · Mainz, DE
• Ozlem Tureci · Homburg, DE
• Petra OEHM · Mainz, DE
• Tana Omokoko · Mainz, DE
• Andrea BREITKREUZ · Worms, DE
• Karolina Anna Mroz · Wiesbaden, DE
• Lisa Hebich · Kerzenheim, DE

Key dates

• Filing date: May 9, 2016
• Grant date: Aug 1, 2023
• Expiry date: Mar 12, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/33
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides Claudin-18.2-specific immunoreceptors (T cell receptors and artificial T cell receptors (chimeric antigen receptors; CARs)) and T cell epitopes which are useful for immunotherapy.