Methods for producing hepatocytes
US11713448B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Jun 16, 2020 |
| Grant date | Aug 1, 2023 |
| Priority date | — |
| Expiry date | Sep 20, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/90
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for producing hepatocytes from pluripotent human stem cells are disclosed herein. The stem cells are plated on a cell culture substrate comprising two laminins. The stem cells are then exposed to different cell culture mediums to induce differentiation. The resulting hepatocytes have higher metabolic capacity compared to hepatocytes cultured on different substrates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.