Plasmid constructs for heterologous protein expression and methods of use
US11713467B2 · kind B2 · utility
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Key dates
| Filing date | Dec 16, 2016 |
| Grant date | Aug 1, 2023 |
| Priority date | — |
| Expiry date | Jun 30, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are plasmid vector constructs encoding multiple immunomodulatory proteins where each protein or component thereof can be expressed utilizing appropriate promotors and/or translation modifiers. Additional immunomodulatory proteins and genetic adjuvants containing shared tumor antigens can be added to further therapeutic potential as well as allow tracking of therapeutic treatment. Also provides are methods of expressing the plasmid constructs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.