T cell receptors that bind to mixed lineage leukemia (MLL)-specific phosphopeptides and methods of use thereof
US11718658B2 · kind B2 · utility
1Cited by
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21Claims
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Key dates
| Filing date | Mar 3, 2020 |
| Grant date | Aug 8, 2023 |
| Priority date | — |
| Expiry date | May 22, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/565
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are TCRs (e.g., TCRs that bind to MLL, e.g., TCRs that bind to an MLL phosphopeptide, e.g., TCRs that bind to an MLL phosphopeptide/MHC complex), cells and pharmaceutical compositions comprising these TCRs, nucleic acids encoding these TCRs, expression vectors and host cells for making these TCRs, and methods of treating a subject using these TCRs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.