Systems and methods for ex-vivo organ care

US11723357B2 · kind B2 · utility

Assignee

• TRANSMEDICS, INC. · US

Inventors

• Waleed H. HASSANEIN · North Andover, US
• Richard Bringham · North Andover, US
• Giovanni Cecere · Needham, US
• Tamer I. KHAYAL · North Andover, US
• Ronald Taylor · Meridian, US
• Hossam Algamil · Scranton, US

Key dates

• Filing date: Nov 18, 2021
• Grant date: Aug 15, 2023
• Expiry date: Nov 18, 2041

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A01N1/143
• WIPO field: Basic materials chemistry
• WIPO sector: Chemistry

Abstract

The disclosure provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the disclosure relates to maintaining an organ ex-vivo at near physiologic conditions. In certain embodiments, the disclosure relates to testing properties of an ex-vivo heart or an organ care system, adjusting a property of the organ care system in response to certain results of the testing, and re-testing the ex-vivo heart or the organ care system. In certain embodiments, the disclosure relates to synchronizing at least one cycle of a pumping of a perfusion fluid with a state of the ex-vivo heart.