Patent · US Active

Hydrophilic berberine-type derivative and application thereof in preparing drug

US11725006B2 · kind B2 · utility

0Cited by

0References

11Claims

0Family size

Assignee

INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES · CN

Inventors

Hailin Qin · Beijing, CN
Lianqiu Wu · Beijing, CN
Xiang Li · Beijing, CN
Haijing ZHANG · Beijing, CN
Li Song · Beijing, CN
Huachen Song · Beijing, CN
Anjun Deng · Beijing, CN
Xiaonan Tang · Beijing, CN
Zhihui Zhang · Katy, US
Zhihong Li · San Jose, US

Key dates

Filing date	Oct 17, 2019
Grant date	Aug 15, 2023
Priority date	—
Expiry date	Oct 17, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D493/22
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

An 8-dihalomethyl berberine-type quaternary ammonium salt compound represented by general formula (I) or (II) and an application thereof in preparing a drug. The compound shows hydrophilicity and has antimicrobial, anti-inflammatory, anti-ulcerative colitis, and antitumor activities, while having no or low toxicity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.