Assessing transplant complication risk with total cell-free DNA

US11725234B2 · kind B2 · utility

Assignee

• The Medical College of Wisconsin, Inc. · US

Inventors

• Aoy Tomita Mitchell · Elm Grove, US
• Michael Mitchell · Elm Grove, US

Key dates

• Filing date: Jun 20, 2018
• Grant date: Aug 15, 2023
• Expiry date: Jun 17, 2039

Classification

• Technology area (CPC —): General

Abstract

This invention relates to methods and compositions for assessing an amount of total cell-free DNA, such as from a transplant subject. The methods and composition provided herein can be used to determine risk of complications following transplantation, including infection, cardiac arrest, and death, in a subject.