Measurement of analytes with membrane channel molecules, and bilayer arrays
US11725238B2 · kind B2 · utility
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22Claims
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Key dates
| Filing date | Jul 20, 2020 |
| Grant date | Aug 15, 2023 |
| Priority date | — |
| Expiry date | Sep 15, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/48721
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to a method for detection of analyte interaction with a channel molecule held in a membrane, comprising the optical detection of a modification in the flux of a signal molecule as it passes through the channel molecule by the action of a membrane potential, wherein the modification in the flux is caused by at least partial blockage of the channel molecule by the analyte. The invention further relates to bilayer arrays, components, methods of manufacture and use.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.