Stable liquid pharmaceutical preparation
US11730698B2 · kind B2 · utility
0Cited by
8References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 18, 2019 |
| Grant date | Aug 22, 2023 |
| Priority date | — |
| Expiry date | Apr 9, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/94
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A stable liquid pharmaceutical formulation according to the present invention includes an antibody or antigen-binding fragment thereof, a surfactant, a sugar or a sugar derivative, a buffer, and a stabilizer. The stable liquid pharmaceutical formulation according to the present invention has low viscosity not only when antibody content is low but also when antibody content is high, and exhibits superior long-term storage stability based on superior stability observed under accelerated conditions and harsh conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.