Patent · US Active

Tetrahydroprotoberberine compound, preparation method therefor and uses thereof, and pharmaceutical composition

US11731965B2 · kind B2 · utility

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1References

4Claims

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Assignees

Inventors

Yang He · Sichuan, CN
Xiangrui Jiang · Shanghai, CN
Jianfeng Li · Qingdao, CN
Yu Wang · Xi'an, CN
Zhen Wang · Shanghai, CN
Weiming Chen · Shanghai, CN
Fuqiang Zhu · Shanghai, CN
Chunhui Wu · Shanghai, CN
Rongxia Zhang · Shanghai, CN
Jingshan Shen · Shanghai, CN
Hualiang Jiang · Shanghai, CN

Key dates

Filing date	Aug 14, 2018
Grant date	Aug 22, 2023
Priority date	—
Expiry date	Aug 14, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D498/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a tetrahydroprotoberberine compound represented by the formula (I), enantiomers, diastereomers, racemates and mixtures thereof, and pharmaceutically acceptable salts, crystalline hydrates and solvates thereof. The invention also provides a method for preparing the compound and the use thereof in the preparation of a medicament for preventing and/or treating central nervous system diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.