Deep ultraviolet-excitable water-solvated polymeric dyes
US11732138B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 28, 2022 |
| Grant date | Aug 22, 2023 |
| Priority date | — |
| Expiry date | Sep 28, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/542
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Water solvated polymeric dyes having a deep ultraviolet excitation spectrum are provided. The subject polymeric dyes include a light harvesting multichromophore having conjugation-modifying repeat units incorporated into the polymer backbone to provide segments of π-conjugated co-monomers having limited π-conjugation between segments. Polymeric tandem dyes are also provided that further include a signaling chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. Also provided are labelled specific binding members that include the subject water solvated polymeric dyes. Methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule in which the subject polymeric dyes find use are also provided. Systems and kits for practicing the subject methods are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.