Anti-CRISPR polynucleotides and polypeptides and methods of use
US11732251B2 · kind B2 · utility
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Key dates
| Filing date | Apr 24, 2018 |
| Grant date | Aug 22, 2023 |
| Priority date | — |
| Expiry date | Apr 30, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2795/10322
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods and compositions are provided for the use of anti-CRISPR (ACR) proteins in plants, including modulation of Cas endonuclease activity, improvement of frequency of homologous recombination, control of Cas endonuclease activity during various cell cycles, spatial and/or temporal regulation of Cas endonuclease activity in plants, usage in gene activation or repression, as well as reduction of off-target polynucleotide cleavage.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.