Patent · US Active

Compounds and methods for the modulation of amyloid-β precursor protein

US11732260B2 · kind B2 · utility

1Cited by

190References

39Claims

0Family size

Assignees

Ionis Pharmaceuticals, Inc. · US
Rosalind Franklin University of Medicine and Science · US

Inventors

Frank Rigo · Carlsbad, US
Michelle L. Hastings · North Chicago, US

Key dates

Filing date	Mar 1, 2019
Grant date	Aug 22, 2023
Priority date	—
Expiry date	Mar 1, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2320/33
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Certain embodiments disclosed herein are directed to compounds and methods for modulating APP expression. In certain embodiments, modulating the splicing of amyloid precursor protein (APP) reduces amyloid β (Aβ) production.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.