Systems and methods to identify transcription factor activation domains and uses thereof
US11732381B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 15, 2021 |
| Grant date | Aug 22, 2023 |
| Priority date | — |
| Expiry date | Jan 27, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06N3/048
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Embodiments herein describe systems and methods to identify transcription factor activation domains and uses thereof. Many embodiments obtain activation measurements of tiles or segments of known transcription factors in an organism. Further embodiments train a machine learning model, such as a convolutional neural network, to identify transcription factors and activation domains in other organisms of the same or different species. Such methods and systems can be used for industrial, medical, and research purposes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.