Compositions and methods for inducing conformational changes in cereblon and other E3 ubiquitin ligases
US11733233B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Jul 21, 2020 |
| Grant date | Aug 22, 2023 |
| Priority date | — |
| Expiry date | Jul 21, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y203/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are compositions, therapeutic methods, screening methods, computational methods and biomarkers based upon the elucidation of the interaction among cereblon, its substrates and certain compounds or agents, including small molecules, peptides, and proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.