Method for reducing paravalvular leaks with decellularized tissue
US11737867B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 16, 2020 |
| Grant date | Aug 29, 2023 |
| Priority date | — |
| Expiry date | Feb 9, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L27/3687
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method for preparing tissue, in particular pericardial tissue, in particular for a heart valve prosthesis, the method including: decellularizing the tissue; subjecting the decellularized tissue to a cross-linking solution including glutaraldehyde; subjecting the tissue to a shape- and structure-stabilizing step, in which the tissue is exposed to a first solution containing glycerol and is exposed to a second solution containing polyethylene glycol; and drying the tissue after the shape- and structure-stabilizing step.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.