Patent · US Active

Processes for preparing a pan-JAK inhibitor and related intermediate compounds

US11739103B2 · kind B2 · utility

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13Claims

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Assignee

Theravance Biopharma R&D IP, LLC · US

Inventors

Norbert Kraut · Seattle, US
Matteo Conza · Thayngen, CH
Anja Huste · Büsingen am Hochrhein, DE
Vit Lellek · Eglisau, CH
Bjorn Gielen · Winterslag, BE
Christian Pater · Mühlhausen-Ehingen, DE
Dimitar Filipov · Elizabeth, US
Xiaojun Huang · Sunnyvale, US
Stephen James Roseblade · St Ives, GB

Key dates

Filing date	Oct 7, 2021
Grant date	Aug 29, 2023
Priority date	—
Expiry date	Feb 12, 2042

Classification

Technology area (CPC B)Performing Operations; Transporting
CPC primaryB01J2531/824
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

The present disclosure provides processes for preparing a crystalline form of 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile and related intermediate compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.