Performance-enhanced protease variants I

US11739310B2 · kind B2 · utility

Assignee

• Henkel AG & Co. KGaA · DE

Inventors

• Nina Mussmann · Willich, DE
• Susanne Wieland · Nievenheim, DE
• Daniela Herbst · Goldkronach, DE
• Inken Prueser · Dressendorf, DE
• Christian Degering · Erkrath, DE
• Daria Strauss · Dressendorf, DE
• Thorsten Eggert · Hattingen, DE
• Christian Leggewie · Mülheim an der Ruhr, DE
• Layla Fernandez · Cologne, DE
• Sabine Griemert · Monheim am Rhein, DE

Key dates

• Filing date: Sep 5, 2018
• Grant date: Aug 29, 2023
• Expiry date: Jun 27, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C11D2111/12
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

An amino acid sequence may have at least 70% sequence identity to the amino acid sequence identified in SEQ ID No. 1 over its entire length, and (a) an amino acid substitution on the position corresponding to the position 271, and (b1) at least one other amino acid substitution for at least one of the positions corresponding to the positions 18, 61, 92, 99, 137, 149, 156, 159, 162, 166, 172, 192, 199, 217, 265, or combinations thereof; and/or (b2) an amino acid substitution on the position corresponding to the position 9, and another amino acid substitution for at least one position corresponding to the positions 29, 48, 101, 130, 31, 133, 144, 217, 224, 252, or combinations thereof. Such proteases are useful for in washing or cleaning agents.