MicroRNA-based compositions and methods used in disease treatment
US11739350B2 · kind B2 · utility
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Key dates
| Filing date | Apr 10, 2019 |
| Grant date | Aug 29, 2023 |
| Priority date | — |
| Expiry date | Apr 10, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/20232
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides a miRNA hairpin that, when processed by a virus-infected cell, increases the therapeutic effectiveness of the virus. The present disclosure also provides a virus encoding such a miRNA hairpin. The present disclosure also provides pre-miRNAs that, when processed by a virus-infected cell, increase extracellular vesicle secretion of the encoded miRNA hairpin by the virus-infected cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.