Systems and methods for processing electronic images to infer biomarkers
US11741604B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 5, 2022 |
| Grant date | Aug 29, 2023 |
| Priority date | — |
| Expiry date | Jul 5, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06V2201/03
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Systems and methods are disclosed for receiving a target electronic image corresponding to a target specimen, the target specimen comprising a tissue sample of a patient, applying a machine learning system to the target electronic image to identify a region of interest of the target specimen and determine an expression level of, category of, and/or presence of a biomarker in the region of interest, the biomarker comprising at least one from among an epithelial growth factor receptor (EGFR) biomarker and/or a DNA mismatch repair (MMR) deficiency biomarker, the machine learning system having been generated by processing a plurality of training images to predict whether a region of interest is present in the target electronic image, the training images comprising images of human tissue and/or images that are algorithmically generated, and outputting the determined expression level of, category of, and/or presence of the biomarker in the region of interest.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.