Metal-porphyrin complexes for the inactivation of the biological activity of opioids

US11744834B2 · kind B2 · utility

Assignee

• The Government of the United States of America, as represented by the Secretary of the Navy · US

Inventors

• Okhil Nag · Alexandria, US
• Gregory Ellis · Silver Spring, US
• Scott Walper · Springfield, US
• Jeffrey R. Deschamps · Laurel, US
• D. Andrew Knight · New Orleans, US
• James B. Delehanty · Washington, US

Key dates

• Filing date: Apr 1, 2020
• Grant date: Sep 5, 2023
• Expiry date: Apr 2, 2041

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/36
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A rhodium-loaded porphyrin complex, comprising the porphyrin (meso-tri(4-sulfonatophenyl) mono(4-carboxyphenyl)porphine (C1S3TPP)) with coordinated with rhodium, effectively neutralizes the biological activity of naturally-occurring and synthetic opioids.