Ultramarine fluorescent protein, construction method therefor and use thereof in preparation of protein sunscreen agent
US11746132B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 21, 2021 |
| Grant date | Sep 5, 2023 |
| Priority date | — |
| Expiry date | Dec 3, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/70
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An ultramarine fluorescent protein, is a protein selected from (a) and (b) protein: (a) a protein consisting of an amino acid sequence set forth in SEQ ID:NO. 2; (b) a protein derived from (a) by substitution, deletion or addition with one or more amino acids in the amino acid sequence of (a) and having activity of the ultramarine fluorescent protein. The ultramarine fluorescent protein (UFP) has the characteristics of pH-insensitivity and light stability, and its chromophore can absorb long-wavelength ultraviolet (UVA) and release fluorescence at wavelength longer than 400 nm. And the aromatic amino acids residue (with content of 9.2%) can absorb medium wavelength ultraviolet (UVB) and release UVA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.