Methods and systems for functional maturation of iPSC and ESC derived cardiomyocytes
US11746328B2 · kind B2 · utility
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Key dates
| Filing date | Mar 3, 2018 |
| Grant date | Sep 5, 2023 |
| Priority date | — |
| Expiry date | Jan 8, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2529/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of inducing functional maturation of immature cardiomyocytes derived from induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs) by electrically pacing the immature cardiomyocytes according to a pulse profile that induces maturation until the immature cardiomyocytes mature into functionally adult cardiomyocytes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.