Patent · US Active

Lactococcus lactis subsp. lactis A32, derived product and use thereof

US11746368B1 · kind B1 · utility

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9Claims
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Key dates

Filing dateSep 2, 2022
Grant dateSep 5, 2023
Priority date
Expiry dateSep 2, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12R2001/46
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention provides a Lactococcus lactis subsp. lactis A32, derived product and use thereof, the present invention falls in the technical field of microorganisms. In the present invention, the Lactococcus lactis subsp. lactis A32 is obtainable by compound mutation on the basis of the original strain L. lactis lxl. Experiments showed that, compared with nisin titre of the original strain L. lactis lxl, the Lactococcus lactis subsp. lactis A32 has high nisin yield, and the nisin titre has been improved for 3˜4 times (over 5066.58 IU/mL); in the meanwhile, the growth curve of the Lactococcus lactis subsp. lactis A32 is slightly longer than the original strain L. lactis lxl and biomass peaks of them are basically consistent. The present invention has laid a foundation for large scale production of nisin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.