Method for producing Ac-225 solution and method for producing medicine using Ac-225 solution
US11752223B2 · kind B2 · utility
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Key dates
| Filing date | Jul 20, 2022 |
| Grant date | Sep 12, 2023 |
| Priority date | — |
| Expiry date | Jul 20, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG21G4/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for producing an 225Ac solution includes a step (I) of irradiating a 226Ra target with particles to generate two or more actinium radioisotopes (Ac) including at least 225Ac, a step (II) of dissolving the 226Ra target after the aforementioned step to obtain a solution (1), a step (III) of separating 226Ra and Ac contained in the solution (1) to obtain a solution (2), a step (IV) of allowing Ac contained in the solution (2) other than 225Ac to decay to obtain a solution (3), and a step (V) of separating Ra and Ac contained in the solution (3) to obtain a solution (4). The solution (4) is used to produce a medicine that contains, as an active ingredient, a conjugate between a chelating agent that has formed a complex with 225Ac, and a targeting agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.