Polymorphs of Selinexor
US11753401B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 5, 2023 |
| Grant date | Sep 12, 2023 |
| Priority date | — |
| Expiry date | Apr 5, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/13
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to crystalline forms of the compound represented by Structural Formula I, and compositions comprising crystalline forms of the compound represented by Structural Formula I described herein. The crystalline forms of the compound of Structural Formula I and compositions comprising the crystalline forms of the compound of Structural Formula I provided herein, in particular, single crystalline Form A, can be incorporated into pharmaceutical compositions, which can be used to treat various disorders associated with CRM1 activity, including cancer. Also described herein are methods for preparing the compound of Structural Formula I and its single crystalline forms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.