Compounds for treating spinal muscular atrophy

US11753407B2 · kind B2 · utility

Assignees

• PTC THERAPEUTICS, INC. · US
• F. Hoffmann-La Roche AG · CH

Inventors

• Hongyan Qi · Plainsboro, US
• Soongyu Choi · Skillman, US
• Amal Dakka · Whitehouse Station, US
• Gary Mitchell Karp · Princeton, US
• Jana Narasimhan · Scotch Plains, US
• Nikolai Naryshkin · East Brunswick Township, US
• Anthony A. Yurpoff
• Marla L. Weetall · Morristown, US
• Ellen Welch · Califon, US
• Matthew G. Woll · Madison, US
• Tianle Yang · Mountainside, US
• Nanjing Zhang · Princeton, US
• Xiaoyan Zhang · Lexington, US
• Xin Zhao · Austin, US
• Luke Green · Basel, CH
• Emmanuel Pinard · Rixheim, FR
• Hasane Ratni · Habsheim, FR

Key dates

• Filing date: Oct 5, 2020
• Grant date: Sep 12, 2023
• Expiry date: Oct 5, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are compounds of Formula (I): and forms thereof, wherein w1, w2, w3, w4, w5, w6 and w7 are as defined herein, including compositions thereof and uses therewith for treating spinal muscular atrophy.