Patent · US Active

Immunoglobulin binding protein, and affinity support using same

US11753449B2 · kind B2 · utility

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1References

13Claims

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Assignees

Inventors

Jun-ichi Yasuoka · Minato, JP
Kiichi Yoshimura · Minato, JP

Key dates

Filing date	Sep 25, 2018
Grant date	Sep 12, 2023
Priority date	—
Expiry date	Apr 26, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P21/02
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Provided are a protein L-derived immunoglobulin binding protein having an increased alkali tolerance, and an affinity support using the same. Disclosed are an immunoglobulin binding protein comprising at least one mutant of an immunoglobulin binding domain, and an affinity support comprising a solid-phase support having the immunoglobulin binding protein bound thereto. A mutant of the immunoglobulin binding domain consists of an amino acid sequence having an identity of at least 85% with the sequence set forth in any one of SEQ ID NO:1 to SEQ ID NO:9 and a predetermined mutation, and the mutant has immunoglobulin κ chain binding activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.