Anti-PD-1/anti-HER2 natural antibody structural heterodimeric bispecific antibody and method of preparing same
US11753471B2 · kind B2 · utility
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Key dates
| Filing date | Feb 8, 2019 |
| Grant date | Sep 12, 2023 |
| Priority date | — |
| Expiry date | Jun 10, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/94
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are an anti-PD-1/anti-HER2 natural antibody structural heterodimeric bispecific antibody and a method of preparing the same. More particularly, provided are a highly stable heterodimeric anti-PD-1/anti-HER2 bispecific antibody having natural IgG characteristics without mismatch between a heavy chain and a light chain, and a method of preparing the same. The bispecific antibody may bind to two target molecules simultaneously and has excellent effects in treatment of a complex disease.
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