Preparation and use of anti-MET-and-RON bispecific antibody and antibody-drug conjugate thereof
US11753477B2 · kind B2 · utility
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Key dates
| Filing date | Feb 10, 2021 |
| Grant date | Sep 12, 2023 |
| Priority date | — |
| Expiry date | Sep 18, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/73
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are a preparation method and use of an anti-MET-and-RON bispecific antibody and an antibody-drug conjugate thereof. The anti-MET-and-RON bispecific antibody includes an anti-MET antibody fragment and an anti-RON antibody fragment which are linked to each other through a specific chemical “knobs-into-holes” structure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.