Methods and devices for generating chemical and gaseous gradients in microfluidic platforms
US11753613B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Nov 7, 2018 |
| Grant date | Sep 12, 2023 |
| Priority date | — |
| Expiry date | Jul 14, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N5/0075
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed herein are devices, methods and compositions for making and using microfluidic devices comprising making a microfluid device comprising one or more channels; and coating at least a portion of an interior surface of at least one channel, wherein one or more gradients are formed by simultaneously introducing into the device a first cellular culture media composition having a certain concentration of a gas, an active agent or both and a second composition having a concentration of a gas, an active agent or both that is/are different from that of the first composition. Such devices are used to investigate cellular responses to physiological states and active agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.