Method for improving productivity of 2′-fucosyllactose through enzymatic treatment
US11753665B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 1, 2022 |
| Grant date | Sep 12, 2023 |
| Priority date | — |
| Expiry date | Nov 1, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y504/02008
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed is a method for improving the productivity of 2′-fucosyllactose (2′-FL) through enzymatic treatment. Lactose used as a substrate in the stationary phase during culture is degraded by treatment with a small amount of enzyme, the resulting glucose is consumed to produce guanosine diphosphate-L-fucose as a precursor of 2′-fucosyllactose, and the use of lactose left after culture can be maximally utilized for the production of 2′-fucosyllactose. As a result, it is possible to increase the productivity of 2′-fucosyllactose in an economically efficient manner because additional glucose is not required while minimizing by-products.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.