Integrated fluidic circuit and device for droplet manipulation and methods thereof
US11759781B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Apr 15, 2022 |
| Grant date | Sep 19, 2023 |
| Priority date | — |
| Expiry date | Apr 15, 2042 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/0688
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Various embodiments of fluidic devices and methods of the present teaching can provide precision on-device loading of fluidic samples, and merging, mixing, and splitting of the fluidic samples, in illustrative embodiments as droplets, using pressures that can be provided by standard laboratory liquid handling equipment. Various embodiments of fluidic devices of the present teachings can provide on-device manipulation of accurate and precise fluidic volumes at the picoliter to nanoliter scale for each steps from fluidic sample loading to fluidic sample splitting. Various embodiments of fluidic elements of the present teachings, for example, but not limited by, various embodiments of fluidic traps of the present teachings, can have a constrained and measurable geometry, allowing for accurate and precise tuning of each fluidic sample volume throughout the on-device liquid handling process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.