Patent · US Active

Adeno-associated virus for activating RNA-NEAT1 over-expression and applications thereof

US11761003B2 · kind B2 · utility

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0References

13Claims

0Family size

Assignee

EYE INSTITUTE OF SHANDONG FIRST MEDICAL UNIVERSITY · CN

Inventors

Weiyun Shi · Qingdao, CN
Qun Wang · Gaithersburg, US
Qingjun Zhou · Sunnyvale, US
Shengqian Dou · Shandong, CN
Hui Jiang · Lo Wu, CN
Bin Zhang · Beijing, CN

Key dates

Filing date	Oct 7, 2022
Grant date	Sep 19, 2023
Priority date	—
Expiry date	Oct 7, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2750/14143
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Long-chain non-coding RNA NEAT1 are used in the preparation of drugs for the treatment of Fuchs' endothelial corneal dystrophy. Overexpression of the long-chain non-coding RNA NEAT1 can effectively reduce corneal endothelial damage, alleviate the symptoms of corneal edema, can be used for the treatment of Fuchs' endothelial corneal malnutrition.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.