Safe harbor loci
US11761004B2 · kind B2 · utility
1Cited by
3References
32Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 8, 2022 |
| Grant date | Sep 19, 2023 |
| Priority date | — |
| Expiry date | Apr 8, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are safe harbor loci and methods for identifying and using safe harbor loci to engineer cells to express transgenes. The safe harbor loci exhibit increased transgene knock-in efficiency and allow for increased, stable expression of transgenes in engineered cells. Guide ribonucleic acids (gRNAs) may be used for insertion of transgenes in the safe harbor loci.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.