Patent · US Active

2,6-dimethoxy-4-(5-phenyl-4-thiophene-2-yl-1H-imidazol-2-yl)-phenol (DPTIP) a small molecule inhibitor of neutral sphingomyelinase 2 (nSMase-2) for the treatment of neurodegenerative and oncologic diseases

US11766423B2 · kind B2 · utility

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Inventors

Barbara Slusher · Kingsville, US
Camilo Rojas · Baltimore, US
Ajit G. Thomas · Baltimore, US
Norman Haughey · Baltimore, US
Marc Ferrer · Potomac, US
Xin Hu · Chestertown, US

Key dates

Filing date	Mar 1, 2019
Grant date	Sep 26, 2023
Priority date	—
Expiry date	Nov 14, 2039

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/28
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Methods for treating one or more diseases associated with neutral sphingomyelinase 2 (nSMase2) in a subject in need of treatment thereof, the method comprising administering to the subject a therapeutically effective amount of 2,6-dimethoxy-4-(5-phenyl-4-thiophen-2-yl-1H-imidazol-2-yl)-phenol (DPTIP) or a pharmaceutically acceptable salt thereof, are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.