Cyclopentathiophene carboxamide derivatives as platelet activating factor receptor antagonists

US11766443B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Matthias Eckhardt · Hannover, DE
• Marina Kristina WILLWACHER · Biberach an der Riß, DE
• Juergen PRESTLE · Biberach an der Riß, DE
• Ferenc KONTES · Biberach an der Riß, DE
• Leo Thomas · Biberach, DE
• Christofer Tautermann · Biberach, DE
• Dieter Wiedenmayer · Biberach an der Riß, DE

Key dates

• Filing date: Nov 12, 2021
• Grant date: Sep 26, 2023
• Expiry date: Nov 12, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to cyclopentathiophene carboxamides of formula (I.0) wherein R1, R2, R3, R4, and n are as defined herein, and pharmaceutically acceptable salts thereof. The invention also relates to the use of the cyclopentathiophene carboxamides of formula (I.0) for the treatment of diseases which can be influenced by antagonizing the activity mediated by the platelet activating factor receptor.