Devices and methods for isolating tumor infiltrating lymphocytes and uses thereof
US11767510B2 · kind B2 · utility
0Cited by
78References
14Claims
0Family size
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Key dates
| Filing date | Apr 29, 2022 |
| Grant date | Sep 26, 2023 |
| Priority date | — |
| Expiry date | Apr 29, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2509/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods for isolating and cryopreserving tumor infiltrating lymphocytes (TILs) and producing therapeutic populations of TILs, including methods via use of a kit and a semi-automatic device for aseptic disaggregation, enrichment, and cryopreservation of a resected tumor prior to expansion of the TIL population. The present invention also provides methods for expansion, and/or stabilization of TILs, for instance UTILs, compositions involving the same and methods of treatment involving the same.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.