Luciferase enzymes for use with thermostable luciferins in bioluminescent assays
US11767517B2 · kind B2 · utility
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26Claims
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Key dates
| Filing date | Jun 5, 2019 |
| Grant date | Sep 26, 2023 |
| Priority date | — |
| Expiry date | Oct 28, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/763
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided herein are enhanced luciferase enzymes for use with thermostable luciferin analogs for bioluminescent assays. In particular, the present disclosure provides compositions, assays, and methods for performing a bioluminescent assay using enhanced, high-activity luciferase enzymes compatible with thermostable luciferins, such as 5,5-disubstituted luciferin analogs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.